Washington: Scientists at Decode Genetics, a subsidiary of American pharma company AMGEN, have discovered a gene with a rare sequence of Parkinson’s disease.
Researchers have identified a rare defect in the function of a gene called ITSN1 that is associated with a higher risk of Parkinson’s disease.
The study, published in Parkinson’s Disease PJ, used whole-genome sequence data from Iceland Decode Genetics, the UK Biobank and the US Accelerating Medicine Partnership Parkinson’s Disease.
A gene called ITSN1 activates a gene called CDC42, which is involved in the regulation of growth and maintenance of dopaminergic neurons.
Accumulation of a gene called ITSN1 is a pathological symptom of Parkinson’s disease, experts said. Researchers suggest that loss of ITSN1 function plays a role in Parkinson’s disease.
